IcsiThe research, presented at the annual conference of the European Society of Human Reproduction and Embryology, also showed that rates of preclinical abortion (defined as a miscarriage so early in the pregnancy that there is no clinical or ultrasound evidence of the pregnancy), miscarriage and overall pregnancy loss during the first trimester remained more or less constant until the age of 34, but increased steadily from the age of 35 onwards.
Dr Dominic Stoop, a senior clinical fellow and gynaecologist, and Ms Eleonora Jansen, an obstetrics and gynaecology resident in training, who are both from the Centre for Reproductive Medicine, UZ Brussel (Brussels, Belgium), and colleagues analysed data on ICSI collected prospectively over 18 years from 1992 to 2009 – a total of 23,354 ovarian stimulation cycles carried out at UZ Brussel. “To our knowledge, there have been no other studies reporting on live birth rates after ICSI in relation to the number of eggs retrieved that also includes the risks for preclinical abortion and miscarriage for women with a positive pregnancy test after ICSI treatment. By focusing only on ICSI treatments, we know the exact number of mature eggs retrieved, fertilised and implanted,” said Dr Stoop.
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